3.5 Pharmaceutics



Omani Frankincense nanoemulsion formulation efficacy and its latent effects on biological aspects of the spiny bollworm (Boisd.).
Metayi MH, Abd El-Naby SS, El-Habal NA, Fahmy HH, Abdou MS, Ali B, Abdel-Rheim KH, Abdel-Megeed A

Front Physiol. 2022;13():1001136.
PMID: 36277209 [PubMed - as supplied by publisher]


Bacterial nanocellulose patches as a carrier for hydrating formulations to improve the topical treatment of nail diseases.
Bellmann T, Luber R, Kischio L, Karl B, Pötzinger Y, Beekmann U, Kralisch D, Wiegand C, Fischer D

Int J Pharm. 2022 Nov;628():122267.
PMID: 36209980 [PubMed - indexed for MEDLINE]


Characterization of Engl Resin as a Potential Use for Pharmaceutical Excipient.
Gashe F, Assefa D, Tesema S, Zeleke G, Tatiparthi R, Kebebe D, Suleman S

Biomed Res Int. 2022;2022():5791308.
PMID: 35978631 [PubMed - indexed for MEDLINE]


Influence of Technological Factors on the Quality of Chitosan Microcapsules with L. Essential Oil.
Pudziuvelyte L, Siauruseviciute A, Morkuniene R, Lazauskas R, Bernatoniene J

Pharmaceutics. 2022 Jun;14(6):.
PMID: 35745831 [PubMed - as supplied by publisher]


Influence of Dietary Supplementation with and on Performance and Blood Biochemistry in Free-Range Leghorn Laying Hens.
Guerrini A, Dalmonte T, Lupini C, Andreani G, Salaroli R, Quaglia G, Zannoni A, Scozzoli M, Forni M, Isani G

Vet Sci. 2022 Apr;9(4):.
PMID: 35448679 [PubMed - as supplied by publisher]


Co-encapsulation of curcumin and boswellic acids in chitosan-coated niosome: an digestion study.
Salehi S, Nourbakhsh MS, Yousefpour M, Rajabzadeh G, Sahab-Negah S

J Microencapsul. 2022 May;39(3):226-238.
PMID: 35384786 [PubMed - indexed for MEDLINE]


Ingredients of a Natural Oral Nutritional Supplement and Their Role in the Treatment of Osteoarthritis.
Bharat KT, Manhas NS, Gutcho J, Lin J, Bhattacharyya S, Kounang R

Clin Med Insights Arthritis Musculoskelet Disord. 2022;15():11795441211063365.
PMID: 35360183 [PubMed - as supplied by publisher]


Synthesis of 3--Acetyl-11-keto-β-boswellic Acid (AKBA)-Derived Amides and Their Mitochondria-Targeted Antitumor Activities.
Li C, He Q, Xu Y, Lou H, Fan P

ACS Omega. 2022 Mar;7(11):9853-9866.
PMID: 35350335 [PubMed - as supplied by publisher]


Safety and efficacy of a feed additive consisting of an extract of olibanum from Roxb. ex Colebr. for use in dogs and horses (FEFANA asbl).
, Bampidis V, Azimonti G, Bastos ML, Christensen H, Fašmon Durjava M, Kouba M, López-Alonso M, López Puente S, Marcon F, Mayo B, Pechová A, Petkova M, Ramos F, Sanz Y, Edoardo Villa R, Woutersen R, Brantom P, Chesson A, Westendorf J, Manini P, Pizzo F, Dusemund B

EFSA J. 2022 Mar;20(3):e07158.
PMID: 35281639 [PubMed - as supplied by publisher]


Dietary Acid Alters the Gut Microbiome and Blood Metabolites in Experimental Models.
Suther C, Daddi L, Bokoliya S, Panier H, Liu Z, Lin Q, Han Y, Chen K, Moore MD, Zhou Y

Nutrients. 2022 Feb;14(4):.
PMID: 35215464 [PubMed - indexed for MEDLINE]


Chemical composition and antimicrobial activity of oleo-gum-resin essential oil extracted by superheated steam.
Ayub MA, Hanif MA, Blanchfield J, Zubair M, Abid MA, Saleh MT

Nat Prod Res. 2022 Feb;():1-6.
PMID: 35200079 [PubMed - as supplied by publisher]


Efficacy of a dietary supplement in dogs with osteoarthritis: A randomized placebo-controlled, double-blind clinical trial.
Martello E, Bigliati M, Adami R, Biasibetti E, Bisanzio D, Meineri G, Bruni N

PLoS One. 2022;17(2):e0263971.
PMID: 35171954 [PubMed - indexed for MEDLINE]


Extract-Loaded Mesoporous Bioactive Glass Nano Particles: Synthesis and Biological Effects.
Ilyas K, Singer L, Akhtar MA, Bourauel CP, Boccaccini AR

Pharmaceutics. 2022 Jan;14(1):.
PMID: 35057022 [PubMed - as supplied by publisher]


  Extract as an Antibiofilm Agent against spp.
Jaroš P, Vrublevskaya M, Lokočová K, Michailidu J, Kolouchová I, Demnerová K

Microorganisms. 2022 Jan;10(1):.
PMID: 35056620 [PubMed - as supplied by publisher]


Reducing Biofilm Infections in Burn Patients' Wounds and Biofilms on Surfaces in Hospitals, Medical Facilities and Medical Equipment to Improve Burn Care: A Systematic Review.
Thomas RE, Thomas BC

Int J Environ Res Public Health. 2021 Dec;18(24):.
PMID: 34948803 [PubMed - indexed for MEDLINE]


Effect of a Selection of Skin Penetration Enhancers on Topical Anti-Inflammatory Effect of Boswellic Acids in Carrageenan-Induced Paw Edema in Rats.
Hajhashemi V, Safaei S

Adv Biomed Res. 2021;10():18.
PMID: 34476226 [PubMed - as supplied by publisher]


Optimization for synthesis of silver nanoparticles through response surface methodology using leaf extract of Boswellia sacra and its application in antimicrobial activity.
Azmi SNH, Al-Jassasi BMH, Al-Sawafi HMS, Al-Shukaili SHG, Rahman N, Nasir M

Environ Monit Assess. 2021 Jul;193(8):497.
PMID: 34286386 [PubMed - indexed for MEDLINE]


A protein-sulfosalicylic acid/boswellic acids @metal-organic framework nanocomposite as anticancer drug delivery system.
Özsoy M, Atiroğlu V, Guney Eskiler G, Atiroğlu A, Deveci Ozkan A, Özacar M

Colloids Surf B Biointerfaces. 2021 Aug;204():111788.
PMID: 33932885 [PubMed - indexed for MEDLINE]


In vitro anti-inflammatory and antioxidant activities of ZnFe O and CrFe O nanoparticles synthesized using Boswellia carteri resin.
Imraish A, Abu Thiab T, Al-Awaida W, Al-Ameer HJ, Bustanji Y, Hammad H, Alsharif M, Al-Hunaiti A

J Food Biochem. 2021 Jun;45(6):e13730.
PMID: 33880765 [PubMed - indexed for MEDLINE]


Modified Bacterial Cellulose Dressings to Treat Inflammatory Wounds.
Beekmann U, Zahel P, Karl B, Schmölz L, Börner F, Gerstmeier J, Werz O, Lorkowski S, Wiegand C, Fischer D, Kralisch D

Nanomaterials (Basel). 2020 Dec;10(12):.
PMID: 33327519 [PubMed - as supplied by publisher]


Antiproliferative effects of boswellic acid-loaded chitosan nanoparticles on human lung cancer cell line A549.
Solanki N, Mehta M, Chellappan DK, Gupta G, Hansbro NG, Tambuwala MM, Aa Aljabali A, Paudel KR, Liu G, Satija S, Hansbro PM, Dua K, Dureja H

Future Med Chem. 2020 Nov;12(22):2019-2034.
PMID: 33124483 [PubMed - indexed for MEDLINE]


-Mediated Silver Nanoparticles Inhibited Acute Myeloid Leukemia (AML) Kasumi-1 Cells by Inducing Cell Cycle Arrest.
Adebayo IA, Usman AI, Shittu FB, Ismail NZ, Arsad H, Muftaudeen TK, Samian MR

Bioinorg Chem Appl. 2020;2020():8898360.
PMID: 33029114 [PubMed - as supplied by publisher]


Formulation of Nanospanlastics as a Promising Approach for ‎Improving the Topical Delivery of a Natural Leukotriene Inhibitor (3-‎Acetyl-11-Keto-β-Boswellic Acid): Statistical Optimization, in vitro ‎Characterization, and ex vivo Permeation Study.
Badria F, Mazyed E

Drug Des Devel Ther. 2020;14():3697-3721.
PMID: 32982176 [PubMed - indexed for MEDLINE]


Influence of boswellic acid on multifunctional properties of chitosan/poly (vinyl alcohol) films for active food packaging.
Narasagoudr SS, Hegde VG, Chougale RB, Masti SP, Dixit S

Int J Biol Macromol. 2020 Jul;154():48-61.
PMID: 32173434 [PubMed - indexed for MEDLINE]


Development of Chitosan-Based Hydrogel Containing Antibiofilm Agents for the Treatment of Staphylococcus aureus-Infected Burn Wound in Mice.
Chhibber T, Gondil VS, Sinha VR

AAPS PharmSciTech. 2020 Jan;21(2):43.
PMID: 31897806 [PubMed - indexed for MEDLINE]


Essential oils of and have effective antidermatophytic activities and that are antagonised by ketoconazole and potentiated in gold nanospheres.
Carmo PHF, Costa MC, Franco PHC, Lage ACP, Rocha CEV, Chaves CR, Faraco AAG, Ladeira LO, Aguilar JLL, César IC, Paixão TA, Resende-Stoianoff MA, Santos DA

Nat Prod Res. 2021 Nov;35(22):4694-4697.
PMID: 31894699 [PubMed - indexed for MEDLINE]


UV-responsive AKBA@ZnO nanoparticles potential for polymorphous light eruption protection and therapy.
Huang X, Nisar MF, Wang M, Wang W, Chen L, Lin M, Xu W, Diao Q, Zhong JL

Mater Sci Eng C Mater Biol Appl. 2020 Feb;107():110254.
PMID: 31761216 [PubMed - indexed for MEDLINE]


A bioinspired 3D shape olibanum-collagen-gelatin scaffolds with tunable porous microstructure for efficient neural tissue regeneration.
Ghorbani F, Zamanian A, Kermanian F, Shamoosi A

Biotechnol Prog. 2020 Jan;36(1):e2918.
PMID: 31576679 [PubMed - indexed for MEDLINE]


Correction to: Metabolic Profile of 3-Acetyl-11-Keto-β-Boswellic Acid and 11-Keto-β-Boswellic Acid in Human Preparations In Vitro, Species Differences, and Bioactivity Variation.
Cui Y, Tian X, Ning J, Wang C, Yu Z, Wang Y, Huo X, Jin L, Deng S, Zhang B, Ma X

AAPS J. 2019 Aug;21(5):100.
PMID: 31414253 [PubMed - as supplied by publisher]


Measurement of 3-acetyl-11-keto-beta-boswellic acid and 11-keto-beta-boswellic acid in Boswellia serrata Supplements Administered to Dogs.
Miscioscia E, Shmalberg J, Scott KC

BMC Vet Res. 2019 Aug;15(1):270.
PMID: 31370899 [PubMed - indexed for MEDLINE]


A novel lecithin-based delivery form of Boswellic acids as complementary treatment of radiochemotherapy-induced cerebral edema in patients with glioblastoma multiforme: a longitudinal pilot experience.
Di Pierro F, Simonetti G, Petruzzi A, Bertuccioli A, Botta L, Bruzzone MG, Cuccarini V, Fariselli L, Lamperti E

J Neurosurg Sci. 2019 Jun;63(3):286-291.
PMID: 31096725 [PubMed - indexed for MEDLINE]


Organic Certification is Not Enough: The Case of the Methoxydecane Frankincense.
Johnson S, DeCarlo A, Satyal P, Dosoky NS, Sorensen A, Setzer WN

Plants (Basel). 2019 Apr;8(4):.
PMID: 30987305 [PubMed - as supplied by publisher]


Dietary Ingredients Requiring Further Research Before Evidence-Based Recommendations Can Be Made for Their Use as an Approach to Mitigating Pain.
Crawford C, Boyd C, Berry K, Deuster P,

Pain Med. 2019 Aug;20(8):1619-1632.
PMID: 30986310 [PubMed - indexed for MEDLINE]


Micellar solubilisation enhances the antiinflammatory activities of curcumin and boswellic acids in rats with adjuvant-induced arthritis.
Khayyal MT, El-Hazek RM, El-Sabbagh WA, Frank J, Behnam D, Abdel-Tawab M

Nutrition. 2018 Oct;54():189-196.
PMID: 30048884 [PubMed - indexed for MEDLINE]


Screening for the anti-inflammation quality markers of Xiaojin Pills based on HPLC-MS/MS method, COX-2 inhibition test and protein interaction network.
Xiong X, He YN, Feng B, Pan Y, Zhang HZ, Ke XM, Zhang Y, Yang M, Han L, Zhang DK

Sci Rep. 2018 May;8(1):7454.
PMID: 29748583 [PubMed - indexed for MEDLINE]


A novel lecithin based delivery form of Boswellic acids (Casperome®) for the management of osteo-muscular pain: a registry study in young rugby players.
Franceschi F, Togni S, Belcaro G, Dugall M, Luzzi R, Ledda A, Pellegrini L, Eggenhoffner R, Giacomelli L

Eur Rev Med Pharmacol Sci. 2016 Oct;20(19):4156-4161.
PMID: 27775780 [PubMed - indexed for MEDLINE]


A single-dose, randomized, cross-over, two-way, open-label study for comparing the absorption of boswellic acids and its lecithin formulation.
Riva A, Morazzoni P, Artaria C, Allegrini P, Meins J, Savio D, Appendino G, Schubert-Zsilavecz M, Abdel-Tawab M

Phytomedicine. 2016 Nov;23(12):1375-1382.
PMID: 27765357 [PubMed - indexed for MEDLINE]


Improved efficacy of cisplatin in combination with a nano-formulation of pentacyclic triterpenediol.
Alam N, Qayum A, Kumar A, Khare V, Sharma PR, Andotra SS, Singh SK, Koul S, Gupta PN

Mater Sci Eng C Mater Biol Appl. 2016 Nov;68():109-116.
PMID: 27524002 [PubMed - indexed for MEDLINE]


Nanoparticle formulation of 11-keto-β-boswellic acid (KBA): anti-inflammatory activity and in vivo pharmacokinetics.
Bairwa K, Jachak SM

Pharm Biol. 2016 Dec;54(12):2909-2916.
PMID: 27305832 [PubMed - indexed for MEDLINE]


Survey on the Quality of the Top-Selling European and American Botanical Dietary Supplements Containing Boswellic Acids.
Meins J, Artaria C, Riva A, Morazzoni P, Schubert-Zsilavecz M, Abdel-Tawab M

Planta Med. 2016 Apr;82(6):573-9.
PMID: 27054914 [PubMed - indexed for MEDLINE]


Carbon Dioxide Expanded Ethanol Extraction: Solubility and Extraction Kinetics of α-Pinene and cis-Verbenol.
Al-Hamimi S, Abellan Mayoral A, Cunico LP, Turner C

Anal Chem. 2016 Apr;88(8):4336-45.
PMID: 27002237 [PubMed - as supplied by publisher]


Development and optimization of boswellic acid-loaded proniosomal gel.
Mehta M, Dureja H, Garg M

Drug Deliv. 2016 Oct;23(8):3072-3081.
PMID: 26953869 [PubMed - indexed for MEDLINE]


Extraction and Characterization of Boswellia Serrata Gum as Pharmaceutical Excipient.
Panta S, Malviya R, Sharma P

Polim Med. 2015;45(1):25-30.
PMID: 26630726 [PubMed - indexed for MEDLINE]


Bioavailability enhancement of a BCS IV compound via an amorphous combination product containing ritonavir.
Miller DA, Keen JM, Brough C, Ellenberger DJ, Cisneros M, Williams RO, McGinity JW

J Pharm Pharmacol. 2016 May;68(5):678-91.
PMID: 26454138 [PubMed - indexed for MEDLINE]


Combination of Anti-Diabetic Drug Metformin and Boswellic Acid Nanoparticles: A Novel Strategy for Pancreatic Cancer Therapy.
Snima KS, Nair RS, Nair SV, Kamath CR, Lakshmanan VK

J Biomed Nanotechnol. 2015 Jan;11(1):93-104.
PMID: 26301303 [PubMed - indexed for MEDLINE]


Enhanced Neuroprotection of Acetyl-11-Keto-β-Boswellic Acid (AKBA)-Loaded O-Carboxymethyl Chitosan Nanoparticles Through Antioxidant and Anti-Inflammatory Pathways.
Ding Y, Qiao Y, Wang M, Zhang H, Li L, Zhang Y, Ge J, Song Y, Li Y, Wen A

Mol Neurobiol. 2016 Aug;53(6):3842-3853.
PMID: 26162321 [PubMed - indexed for MEDLINE]


Comparative studies of pharmacokinetics and anticoagulatory effect in rats after oral administration of Frankincense and its processed products.
Pan YN, Liang XX, Niu LY, Wang YN, Tong X, Hua HM, Zheng J, Meng DY, Liu XQ

J Ethnopharmacol. 2015 Aug;172():118-23.
PMID: 26117531 [PubMed - indexed for MEDLINE]


Gastroretentive Matrix Tablets of Boswellia Oleogum Resin: Preparation, Optimization, In Vitro Evaluation, and Cytoprotective Effect on Indomethacin-Induced Gastric Ulcer in Rabbits.
Yusif RM, Abu Hashim II, Mohamed EA, Badria FA

AAPS PharmSciTech. 2016 Apr;17(2):328-38.
PMID: 26092303 [PubMed - indexed for MEDLINE]


Boswellia carterii liquisolid systems with promoted anti-inflammatory activity.
Mostafa DM, Ammar NM, Abd El-Alim SH, Kassem AA, Hussein RA, Awad G, El-Awdan SA

Curr Drug Deliv. 2015;12(4):454-63.
PMID: 25895614 [PubMed - indexed for MEDLINE]


Development and optimisation of 3-Acetyl-11-keto-β-boswellic acid loaded poly-lactic-co-glycolic acid-nanoparticles with enhanced oral bioavailability and in-vivo anti-inflammatory activity in rats.
Bairwa K, Jachak SM

J Pharm Pharmacol. 2015 Sep;67(9):1188-97.
PMID: 25851251 [PubMed - indexed for MEDLINE]


Boswellia gum resin/chitosan polymer composites: Controlled delivery vehicles for aceclofenac.
Jana S, Laha B, Maiti S

Int J Biol Macromol. 2015;77():303-6.
PMID: 25825076 [PubMed - indexed for MEDLINE]


Prospects of boswellic acids as potential pharmaceutics.
Du Z, Liu Z, Ning Z, Liu Y, Song Z, Wang C, Lu A

Planta Med. 2015 Mar;81(4):259-71.
PMID: 25714728 [PubMed - indexed for MEDLINE]


A cosmeceutical formulation based on boswellic acids for the treatment of erythematous eczema and psoriasis.
Togni S, Maramaldi G, Di Pierro F, Biondi M

Clin Cosmet Investig Dermatol. 2014;7():321-7.
PMID: 25419153 [PubMed - as supplied by publisher]


Transdermal microemulsions of Boswellia carterii Bird: formulation, characterization and in vivo evaluation of anti-inflammatory activity.
Mostafa DM, Ammar NM, Basha M, Hussein RA, El Awdan S, Awad G

Drug Deliv. 2015;22(6):748-56.
PMID: 24725029 [PubMed - indexed for MEDLINE]


Investigating permeability related hurdles in oral delivery of 11-keto-β-boswellic acid.
Bagul P, Khomane KS, Bansal AK

Int J Pharm. 2014 Apr;464(1-2):104-10.
PMID: 24463070 [PubMed - indexed for MEDLINE]


Preparation of amorphous solid dispersions by rotary evaporation and KinetiSol Dispersing: approaches to enhance solubility of a poorly water-soluble gum extract.
Bennett RC, Brough C, Miller DA, O'Donnell KP, Keen JM, Hughey JR, Williams RO, McGinity JW

Drug Dev Ind Pharm. 2015 Mar;41(3):382-97.
PMID: 24329130 [PubMed - indexed for MEDLINE]


Preparation and characterization of solid lipid nanoparticles loaded with frankincense and myrrh oil.
Shi F, Zhao JH, Liu Y, Wang Z, Zhang YT, Feng NP

Int J Nanomedicine. 2012;7():2033-43.
PMID: 22619540 [PubMed - indexed for MEDLINE]


Pharmacology of an extract of salai guggal ex-Boswellia serrata, a new non-steroidal anti-inflammatory agent.
Singh GB, Atal CK

Agents Actions. 1986 Jun;18(3-4):407-12.
PMID: 3751752 [PubMed - indexed for MEDLINE]