11. Pharmakokinetik

Publikationen

1. Increased Bioavailability of 11-Keto-β-Boswellic Acid Following Single Oral Dose Frankincense Extract Administration After a Standardized Meal in Healthy Male Volunteers: Modeling and Simulation Considerations for Evaluating Drug Exposures.
Skarke C, Kuczka K, Tausch L, Werz O, Rossmanith T, Barrett JS, Harder S, Holtmeier W, Schwarz JA

J Clin Pharmacol. 2011 Dec;0(0):0.
PMID: 22167571 [PubMed - as supplied by publisher]

2. Pharmakokinetische Arzneimittelinteraktionen zwischen Tumortherapeutika und Arzneimitteln der Komplementären Medizin: Mechanismen und klinische Relevanz.
Unger M

Forsch Komplementmed. 2011;18(4):213-8.
PMID: 21934321 [PubMed - as supplied by publisher]

3. Determination of major boswellic acids in plasma by high-pressure liquid chromatography/mass spectrometry.
Gerbeth K, Meins J, Kirste S, Momm F, Schubert-Zsilavecz M, Abdel-Tawab M

J Pharm Biomed Anal. 2011 Dec;56(5):998-1005.
PMID: 21855244 [PubMed - indexed for MEDLINE]

4. A new Bacillus megaterium whole-cell catalyst for the hydroxylation of the pentacyclic triterpene 11-keto-β-boswellic acid (KBA) based on a recombinant cytochrome P450 system.
Bleif S, Hannemann F, Zapp J, Hartmann D, Jauch J, Bernhardt R

Appl Microbiol Biotechnol. 2012 Feb;93(3):1135-46.
PMID: 21779845 [PubMed - as supplied by publisher]

5. Complexation with phosphatidyl choline as a strategy for absorption enhancement of boswellic acid.
Sharma A, Gupta NK, Dixit VK

Drug Deliv. 2010 Nov;17(8):587-95.
PMID: 20624027 [PubMed - indexed for MEDLINE]

6. 3-Acetyl-11-keto-beta-boswellic acid loaded-polymeric nanomicelles for topical anti-inflammatory and anti-arthritic activity.
Goel A, Ahmad FJ, Singh RM, Singh GN

J Pharm Pharmacol. 2010 Feb;62(2):273-8.
PMID: 20487208 [PubMed - indexed for MEDLINE]

7. Permeation of Boswellia extract in the Caco-2 model and possible interactions of its constituents KBA and AKBA with OATP1B3 and MRP2.
Krüger P, Kanzer J, Hummel J, Fricker G, Schubert-Zsilavecz M, Abdel-Tawab M

Eur J Pharm Sci. 2009 Feb;36(2-3):275-84.
PMID: 19010411 [PubMed - indexed for MEDLINE]

8. Metabolism of boswellic acids in vitro and in vivo.
Krüger P, Daneshfar R, Eckert GP, Klein J, Volmer DA, Bahr U, Müller WE, Karas M, Schubert-Zsilavecz M, Abdel-Tawab M

Drug Metab Dispos. 2008 Jun;36(6):1135-42.
PMID: 18356270 [PubMed - indexed for MEDLINE]

9. Estimation of boswellic acids from market formulations of Boswellia serrata extract and 11-keto beta-boswellic acid in human plasma by high-performance thin-layer chromatography.
Shah SA, Rathod IS, Suhagia BN, Patel DA, Parmar VK, Shah BK, Vaishnavi VM

J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Apr;848(2):232-8.
PMID: 17101304 [PubMed - indexed for MEDLINE]

10. Compression coated systems for colonic delivery of 5-fluorouracil.
Sinha VR, Singh A, Singh S, Bhinge JR

J Pharm Pharmacol. 2007 Mar;59(3):359-65.
PMID: 17331338 [PubMed - indexed for MEDLINE]

11. Modulation of Pgp function by boswellic acids.
Weber CC, Reising K, Müller WE, Schubert-Zsilavecz M, Abdel-Tawab M

Planta Med. 2006 May;72(6):507-13.
PMID: 16773534 [PubMed - indexed for MEDLINE]

12. Analysis of frankincense from various Boswellia species with inhibitory activity on human drug metabolising cytochrome P450 enzymes using liquid chromatography mass spectrometry after automated on-line extraction.
Frank A, Unger M

J Chromatogr A. 2006 Apr;1112(1-2):255-62.
PMID: 16364338 [PubMed - indexed for MEDLINE]

13. High-performance liquid chromatographic determination of acetyl-11-keto-alpha-boswellic acid, a novel pentacyclic triterpenoid, in plasma using a fluorinated stationary phase and photodiode array detection: application in pharmacokinetic studies.
Büchele B, Zugmaier W, Genze F, Simmet T

J Chromatogr B Analyt Technol Biomed Life Sci. 2005 Dec;829(1-2):144-8.
PMID: 16266833 [PubMed - indexed for MEDLINE]

14. Determination of boswellic acids in brain and plasma by high-performance liquid chromatography/tandem mass spectrometry.
Reising K, Meins J, Bastian B, Eckert G, Mueller WE, Schubert-Zsilavecz M, Abdel-Tawab M

Anal Chem. 2005 Oct;77(20):6640-5.
PMID: 16223251 [PubMed - indexed for MEDLINE]

15. Effect of food intake on the bioavailability of boswellic acids from a herbal preparation in healthy volunteers.
Sterk V, Büchele B, Simmet T

Planta Med. 2004 Dec;70(12):1155-60.
PMID: 15643550 [PubMed - indexed for MEDLINE]

16. Pharmacokinetic study of 11-Keto beta-Boswellic acid.
Sharma S, Thawani V, Hingorani L, Shrivastava M, Bhate VR, Khiyani R

Phytomedicine. 2004 Feb;11(2-3):255-60.
PMID: 15070181 [PubMed - indexed for MEDLINE]

17. Analysis of 12 different pentacyclic triterpenic acids from frankincense in human plasma by high-performance liquid chromatography and photodiode array detection.
Büchele B, Simmet T

J Chromatogr B Analyt Technol Biomed Life Sci. 2003 Oct;795(2):355-62.
PMID: 14522040 [PubMed - indexed for MEDLINE]

18. Determination of 11-keto-boswellic acid in human plasma.
Kaunzinger A, Baumeister A, Cuda K, Häring N, Schug B, Blume HH, Raddatz K, Fischer G, Schubert-Zsilavecz M

J Pharm Biomed Anal. 2002 May;28(3-4):729-39.
PMID: 12008153 [PubMed - indexed for MEDLINE]

19. Development of a high-performance liquid chromatographic method for the determination of 11-keto-beta-boswellic acid in human plasma.
Tawab MA, Kaunzinger A, Bahr U, Karas M, Wurglics M, Schubert-Zsilavecz M

J Chromatogr B Biomed Sci Appl. 2001 Sep;761(2):221-7.
PMID: 11587352 [PubMed - indexed for MEDLINE]