11.2 Rheumatoide Erkrankungen

Anfang der 90er Jahre wurden eine Reihe nichtpublizierter Studien vorgestellt, die meist eine Wirksamkeit von Boswelliaextrakten (u.a. H 15 Ayurmedica) bei rheumatoider Arthritis nahe legen:

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Eine weitere Studie zur Osteoarthritis erschien 2003 von Kimmatkar et al.:

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Publikationen

1.

Benefits of a Food Supplement Containing and Bromelain for Improving the Quality of Life in Patients with Osteoarthritis: A Pilot Study.
Italiano G, Raimondo M, Giannetti G, Gargiulo A

J Altern Complement Med. 2019 Nov;():.
PMID: 31674795 [PubMed - as supplied by publisher]

2.

Pumpkin seeds, Centella asiatica, Boswellia, Helichrysum, acetate vitamin E, Melaleuca alternifolia and hyaluronic acid phytocomplex monotherapy effects in patients with chronic pelvic pain syndrome.
Di Vico T, Durante J, Polito C, Tognarelli A, Canale D, Caglieresi C, Morelli G, Bartoletti R

Minerva Urol Nefrol. 2019 Sep;():.
PMID: 31558010 [PubMed - as supplied by publisher]

3.

A pilot, randomized, double-blind, placebo-controlled trial to assess the safety and efficacy of a novel Boswellia serrata extract in the management of osteoarthritis of the knee.
Majeed M, Majeed S, Narayanan NK, Nagabhushanam K

Phytother Res. 2019 May;33(5):1457-1468.
PMID: 30838706 [PubMed - indexed for MEDLINE]

4.

An Anecdote About Arthritis and Boswellia serrata.
Shader RI

Clin Ther. 2018 05;40(5):669-671.
PMID: 29735296 [PubMed - as supplied by publisher]

5.

A Placebo-Controlled Double-Blind Study Demonstrates the Clinical Efficacy of a Novel Herbal Formulation for Relieving Joint Discomfort in Human Subjects with Osteoarthritis of Knee.
Karlapudi V, Prasad Mungara AVV, Sengupta K, Davis BA, Raychaudhuri SP

J Med Food. 2018 May;21(5):511-520.
PMID: 29708818 [PubMed - indexed for MEDLINE]

6.

Efficacy of curcumin and Boswellia for knee osteoarthritis: Systematic review and meta-analysis.
Bannuru RR, Osani MC, Al-Eid F, Wang C

Semin Arthritis Rheum. 2018 12;48(3):416-429.
PMID: 29622343 [PubMed - indexed for MEDLINE]

7.

Phytoproflex®: supplementary management of osteoarthrosis: a supplement registry.
Belcaro G, Dugall M, Luzzi R, Hosoi M, Ledda A, Feragalli B, Hu S, Ganguly A, Eggenhoffner R, Corti A, Giacomelli L

Minerva Med. 2018 Apr;109(2):88-94.
PMID: 29534559 [PubMed - indexed for MEDLINE]

8.

Efficacy and safety of curcumin and its combination with boswellic acid in osteoarthritis: a comparative, randomized, double-blind, placebo-controlled study.
Haroyan A, Mukuchyan V, Mkrtchyan N, Minasyan N, Gasparyan S, Sargsyan A, Narimanyan M, Hovhannisyan A

BMC Complement Altern Med. 2018 Jan;18(1):7.
PMID: 29316908 [PubMed - indexed for MEDLINE]

9.

Dietary supplements for treating osteoarthritis: a systematic review and meta-analysis.
Liu X, Machado GC, Eyles JP, Ravi V, Hunter DJ

Br J Sports Med. 2018 Feb;52(3):167-175.
PMID: 29018060 [PubMed - indexed for MEDLINE]

10.

Oral herbal medicines marketed in Brazil for the treatment of osteoarthritis: A systematic review and meta-analysis.
Del Grossi Moura M, Lopes LC, Biavatti MW, Kennedy SA, de Oliveira E Silva MC, Silva MT, de Cássia Bergamaschi C

Phytother Res. 2017 Nov;31(11):1676-1685.
PMID: 28872719 [PubMed - indexed for MEDLINE]

11.

Evaluation of the effect of Elaeagnus angustifolia alone and combined with Boswellia thurifera compared with ibuprofen in patients with knee osteoarthritis: a randomized double-blind controlled clinical trial.
Karimifar M, Soltani R, Hajhashemi V, Sarrafchi S

Clin Rheumatol. 2017 Aug;36(8):1849-1853.
PMID: 28349271 [PubMed - indexed for MEDLINE]

12.

Phytomedicine in Joint Disorders.
Dragos D, Gilca M, Gaman L, Vlad A, Iosif L, Stoian I, Lupescu O

Nutrients. 2017 Jan;9(1):.
PMID: 28275210 [PubMed - indexed for MEDLINE]

13.

Five Herbs Plus Thiamine Reduce Pain and Improve Functional Mobility in Patients With Pain: A Pilot Study.
Hedaya R

Altern Ther Health Med. 2017 Jan;23(1):14-19.
PMID: 28160759 [PubMed - indexed for MEDLINE]

14.

Movardol® (N-acetylglucosamine, Boswellia serrata, ginger) supplementation in the management of knee osteoarthritis: preliminary results from a 6-month registry study.
Bolognesi G, Belcaro G, Feragalli B, Cornelli U, Cotellese R, Hu S, Dugall M

Eur Rev Med Pharmacol Sci. 2016 12;20(24):5198-5204.
PMID: 28051248 [PubMed - indexed for MEDLINE]

15.

Management strategies for knee osteoarthritis: Aflapin ().
Suva MA, Kheni DB, Sureja VP

Ayu. 2017 Jan-Jun;38(1-2):94.
PMID: 29861602 [PubMed - as supplied by publisher]

16.

In Vivo Osteoinduction: Evaluating 2-Beta Coxatene as an Immunoinductive Compound and Novel Ingredient for Joint Support.
Spinks K, Scaffidi JJ

Integr Med (Encinitas). 2016 Oct;15(5):34-44.
PMID: 27980494 [PubMed - as supplied by publisher]

17.

A novel lecithin based delivery form of Boswellic acids (Casperome®) for the management of osteo-muscular pain: a registry study in young rugby players.
Franceschi F, Togni S, Belcaro G, Dugall M, Luzzi R, Ledda A, Pellegrini L, Eggenhoffner R, Giacomelli L

Eur Rev Med Pharmacol Sci. 2016 10;20(19):4156-4161.
PMID: 27775780 [PubMed - indexed for MEDLINE]

18.

Clinical comparison of oral administration and viscosupplementation of hyaluronic acid (HA) in early knee osteoarthritis.
Ricci M, Micheloni GM, Berti M, Perusi F, Sambugaro E, Vecchini E, Magnan B

Musculoskelet Surg. 2017 Apr;101(1):45-49.
PMID: 27681813 [PubMed - indexed for MEDLINE]

19.

Nutraceutical supplement in the management of tendinopathies: a systematic review.
Fusini F, Bisicchia S, Bottegoni C, Gigante A, Zanchini F, Busilacchi A

Muscles Ligaments Tendons J. 2016 Jan-Mar;6(1):48-57.
PMID: 27331031 [PubMed - as supplied by publisher]

20.

Benefits of antioxidant supplements for knee osteoarthritis: rationale and reality.
Grover AK, Samson SE

Nutr J. 2016 Jan;15():1.
PMID: 26728196 [PubMed - indexed for MEDLINE]

21.

Methylsulfonylmethane and boswellic acids versus glucosamine sulfate in the treatment of knee arthritis: Randomized trial.
Notarnicola A, Maccagnano G, Moretti L, Pesce V, Tafuri S, Fiore A, Moretti B

Int J Immunopathol Pharmacol. 2016 Mar;29(1):140-6.
PMID: 26684635 [PubMed - indexed for MEDLINE]

22.

Hand 'stress' arthritis in young subjects: effects of Flexiqule (pharma-standard Boswellia extract). A preliminary case report.
Belcaro G, Feragalli B, Cornelli U, Dugall M

Minerva Gastroenterol Dietol. 2015 Oct;():.
PMID: 26492590 [PubMed - as supplied by publisher]

23.

Management of osteoarthritis (OA) with the pharma-standard supplement FlexiQule (Boswellia): a 12-week registry.
Belcaro G, Dugall M, Luzzi R, Ledda A, Pellegrini L, Hu S, Ippolito E

Minerva Gastroenterol Dietol. 2015 Oct;():.
PMID: 26492586 [PubMed - as supplied by publisher]

24.

Effect of Sri Lankan traditional medicine and Ayurveda on Sandhigata Vata (osteoarthritis of knee joint).
Perera PK, Perera M, Kumarasinghe N

Ayu. 2014 Oct-Dec;35(4):411-5.
PMID: 26195904 [PubMed - as supplied by publisher]

25.

FlexiQule (Boswellia extract) in the supplementary management of osteoarthritis: a supplement registry.
Belcaro G, Dugall M, Luzzi R, Ledda A, Pellegrini L, Cesarone MR, Hosoi M, Errichi M, Francis S, Cornelli U

Minerva Med. 2014 Dec;105(6 Suppl 2):9-16.
PMID: 26076376 [PubMed - indexed for MEDLINE]

26.

Co-analgesic therapy for arthroscopic supraspinatus tendon repair pain using a dietary supplement containing Boswellia serrata and Curcuma longa: a prospective randomized placebo-controlled study.
Merolla G, Dellabiancia F, Ingardia A, Paladini P, Porcellini G

Musculoskelet Surg. 2015 Sep;99 Suppl 1():S43-52.
PMID: 25957549 [PubMed - indexed for MEDLINE]

27.

A medicinal herb-based natural health product improves the condition of a canine natural osteoarthritis model: a randomized placebo-controlled trial.
Moreau M, Lussier B, Pelletier JP, Martel-Pelletier J, Bédard C, Gauvin D, Troncy E

Res Vet Sci. 2014 Dec;97(3):574-81.
PMID: 25311158 [PubMed - indexed for MEDLINE]

28.

Oral herbal therapies for treating osteoarthritis.
Cameron M, Chrubasik S

Cochrane Database Syst Rev. 2014 May;(5):CD002947.
PMID: 24848732 [PubMed - indexed for MEDLINE]

29.

A commercialized dietary supplement alleviates joint pain in community adults: a double-blind, placebo-controlled community trial.
Nieman DC, Shanely RA, Luo B, Dew D, Meaney MP, Sha W

Nutr J. 2013 Nov;12(1):154.
PMID: 24274358 [PubMed - indexed for MEDLINE]

30.

Clinical evaluation of a formulation containing Curcuma longa and Boswellia serrata extracts in the management of knee osteoarthritis.
Kizhakkedath R

Mol Med Rep. 2013 Nov;8(5):1542-8.
PMID: 24002213 [PubMed - indexed for MEDLINE]

31.

Ayurvedic medicine offers a good alternative to glucosamine and celecoxib in the treatment of symptomatic knee osteoarthritis: a randomized, double-blind, controlled equivalence drug trial.
Chopra A, Saluja M, Tillu G, Sarmukkaddam S, Venugopalan A, Narsimulu G, Handa R, Sumantran V, Raut A, Bichile L, Joshi K, Patwardhan B

Rheumatology (Oxford). 2013 Aug;52(8):1408-17.
PMID: 23365148 [PubMed - indexed for MEDLINE]

32.

Clinical evaluation of Boswellia serrata (Shallaki) resin in the management of Sandhivata (osteoarthritis).
Gupta PK, Samarakoon SM, Chandola HM, Ravishankar B

Ayu. 2011 Oct;32(4):478-82.
PMID: 22661840 [PubMed - as supplied by publisher]

33.

A double blind, randomized, placebo controlled clinical study evaluates the early efficacy of aflapin in subjects with osteoarthritis of knee.
Vishal AA, Mishra A, Raychaudhuri SP

Int J Med Sci. 2011;8(7):615-22.
PMID: 22022214 [PubMed - indexed for MEDLINE]

34.

The "MESACA" study: methylsulfonylmethane and boswellic acids in the treatment of gonarthrosis.
Notarnicola A, Tafuri S, Fusaro L, Moretti L, Pesce V, Moretti B

Adv Ther. 2011 Oct;28(10):894-906.
PMID: 21986780 [PubMed - indexed for MEDLINE]

35.

Antiarthritic activity of a standardized, multiherbal, Ayurvedic formulation containing Boswellia serrata: in vitro studies on knee cartilage from osteoarthritis patients.
Sumantran VN, Joshi AK, Boddul S, Koppikar SJ, Warude D, Patwardhan B, Chopra A, Chandwaskar R, Wagh UV

Phytother Res. 2011 Sep;25(9):1375-80.
PMID: 25363757 [PubMed - indexed for MEDLINE]

36.

Comparative efficacy and tolerability of 5-Loxin and AflapinAgainst osteoarthritis of the knee: a double blind, randomized, placebo controlled clinical study.
Sengupta K, Krishnaraju AV, Vishal AA, Mishra A, Trimurtulu G, Sarma KV, Raychaudhuri SK, Raychaudhuri SP

Int J Med Sci. 2010 Nov;7(6):366-77.
PMID: 21060724 [PubMed - indexed for MEDLINE]

37.

A double blind, randomized, placebo controlled study of the efficacy and safety of 5-Loxin for treatment of osteoarthritis of the knee.
Sengupta K, Alluri KV, Satish AR, Mishra S, Golakoti T, Sarma KV, Dey D, Raychaudhuri SP

Arthritis Res Ther. 2008;10(4):R85.
PMID: 18667054 [PubMed - indexed for MEDLINE]

38.

Nutraceuticals in the management of osteoarthritis.
Clayton JJ

Orthopedics. 2007 08;30(8):624-9; quiz 630-1.
PMID: 17727018 [PubMed - indexed for MEDLINE]

39.

Natural products as a gold mine for arthritis treatment.
Khanna D, Sethi G, Ahn KS, Pandey MK, Kunnumakkara AB, Sung B, Aggarwal A, Aggarwal BB

Curr Opin Pharmacol. 2007 Jun;7(3):344-51.
PMID: 17475558 [PubMed - indexed for MEDLINE]

40.

Evidence of effectiveness of herbal antiinflammatory drugs in the treatment of painful osteoarthritis and chronic low back pain.
Chrubasik JE, Roufogalis BD, Chrubasik S

Phytother Res. 2007 Jul;21(7):675-83.
PMID: 17444576 [PubMed - indexed for MEDLINE]

41.

A 32-week randomized, placebo-controlled clinical evaluation of RA-11, an Ayurvedic drug, on osteoarthritis of the knees.
Chopra A, Lavin P, Patwardhan B, Chitre D

J Clin Rheumatol. 2004 Oct;10(5):236-45.
PMID: 17043520 [PubMed - as supplied by publisher]

42.

Dietary support with Boswellia resin in canine inflammatory joint and spinal disease.
Reichling J, Schmökel H, Fitzi J, Bucher S, Saller R

Schweiz Arch Tierheilkd. 2004 Feb;146(2):71-9.
PMID: 14994484 [PubMed - indexed for MEDLINE]

43.

Efficacy and tolerability of Boswellia serrata extract in treatment of osteoarthritis of knee--a randomized double blind placebo controlled trial.
Kimmatkar N, Thawani V, Hingorani L, Khiyani R

Phytomedicine. 2003 Jan;10(1):3-7.
PMID: 12622457 [PubMed - indexed for MEDLINE]

44.

[Is H15 (resin extract of Boswellia serrata, "incense") a useful supplement to established drug therapy of chronic polyarthritis? Results of a double-blind pilot study].
Sander O, Herborn G, Rau R

Z Rheumatol. 1998 Feb;57(1):11-6.
PMID: 9566100 [PubMed - indexed for MEDLINE]

45.

Special extract of BOSWELLIA serrata (H 15) in the treatment of rheumatoid arthritis.
Etzel R

Phytomedicine. 1996 May;3(1):91-4.
PMID: 23194870 [PubMed - as supplied by publisher]

46.

Treatment of osteoarthritis with a herbomineral formulation: a double-blind, placebo-controlled, cross-over study.
Kulkarni RR, Patki PS, Jog VP, Gandage SG, Patwardhan B

J Ethnopharmacol. 1991 May-Jun;33(1-2):91-5.
PMID: 1943180 [PubMed - indexed for MEDLINE]