9. Toxicity / Side Effects/



Antimicrobial Activity of Frankincense () Oil and Smoke against Pathogenic and Airborne Microbes.
Al-Kharousi ZS, Mothershaw AS, Nzeako B

Foods. 2023 Sep;12(18):.
PMID: 37761150 [PubMed - as supplied by publisher]


Treatment of adverse radiation effects with Boswellia serrata after failure of pentoxifylline and vitamin E: illustrative cases.
Warnick RE

J Neurosurg Case Lessons. 2023 Jan;5(5):.
PMID: 36718863 [PubMed - as supplied by publisher]


Complementary medicines used in ulcerative colitis and unintended interactions with cytochrome P450-dependent drug-metabolizing enzymes.
Şen A

Turk J Med Sci. 2022 Oct;52(5):1425-1447.
PMID: 36422483 [PubMed - indexed for MEDLINE]


Single-Center-Single-Blinded Clinical Trial to Evaluate the Efficacy of a Nutraceutical Containing Boswellia Serrata, Bromelain, Zinc, Magnesium, Honey, Tyndallized Lactobacillus Acidophilus and Casei to Fight Upper Respiratory Tract Infection and Otitis Media.
Della Volpe A, De Luca P, De Lucia A, Martines F, Piroli P, D'Ascanio L, Camaioni A, La Mantia I, Di Stadio A

Healthcare (Basel). 2022 Aug;10(8):.
PMID: 36011184 [PubMed - as supplied by publisher]


Acute and sub chronic toxicity studies with herbal pain relieving formula (Rhuleave-K™) in rats.
Antony B, Benny M, Kuruvilla BT, Gupta NK, Jacob S

Regul Toxicol Pharmacol. 2022 Aug;133():105214.
PMID: 35781033 [PubMed - indexed for MEDLINE]


Safety and efficacy of a feed additive consisting of an extract of olibanum from Roxb. ex Colebr. for use in dogs and horses (FEFANA asbl).
, Bampidis V, Azimonti G, Bastos ML, Christensen H, Fašmon Durjava M, Kouba M, López-Alonso M, López Puente S, Marcon F, Mayo B, Pechová A, Petkova M, Ramos F, Sanz Y, Edoardo Villa R, Woutersen R, Brantom P, Chesson A, Westendorf J, Manini P, Pizzo F, Dusemund B

EFSA J. 2022 Mar;20(3):e07158.
PMID: 35281639 [PubMed - as supplied by publisher]


Safety assessment of a novel water-soluble extract of gum resin: acute toxicity, 90-day sub-chronic toxicity, Ames' bacterial reverse mutation, and micronucleus assays.
Dodda S, Madireddy RK, Alluri VK, Golakoti T, Sengupta K

Toxicol Mech Methods. 2022 Jun;32(5):362-372.
PMID: 34886755 [PubMed - indexed for MEDLINE]


Allergic contact dermatitis from Boswellia carterii (frankincense) oil.
Buonomo M, Hylwa S

Contact Dermatitis. 2021 Oct;85(4):465-467.
PMID: 33963563 [PubMed - indexed for MEDLINE]


Haematotoxic effects of methanolic extract of oleo gum resin (frankinccense) in rats.
Alyahya AAI, Asad M, Asdaq SMB, Mohzari Y, Alrashed A, Alajami HN, Aljohani AO, Al Mushtawi AA, Alajmi A, Alajmi HN

Sci Prog. 2021;104(2):368504211015102.
PMID: 33949902 [PubMed - indexed for MEDLINE]


Repeated 28-DAY oral dose study on Boswellia sacra oleo gum resin extract for testicular toxicity in rats.
Alyahya AAI, Asad M

J Ethnopharmacol. 2020 Aug;258():112890.
PMID: 32330512 [PubMed - indexed for MEDLINE]


11-Keto-β-Boswellic Acid Attenuates Glutamate Release and Kainic Acid-Induced Excitotoxicity in the Rat Hippocampus.
Lu CW, Lin TY, Wang SJ

Planta Med. 2020 Apr;86(6):434-441.
PMID: 32097973 [PubMed - indexed for MEDLINE]


Repeat oral dose safety study of standardized methanolic extract of Boswellia sacra oleo gum resin in rats.
Al-Yahya AAI, Asad M, Sadaby A, Alhussaini MS

Saudi J Biol Sci. 2020 Jan;27(1):117-123.
PMID: 31889825 [PubMed - as supplied by publisher]


Induction of developmental toxicity and cardiotoxicity in zebrafish embryos/larvae by acetyl-11-keto-β-boswellic acid (AKBA) through oxidative stress.
Han L, Xia Q, Zhang L, Zhang X, Li X, Zhang S, Wang L, Liu C, Liu K

Drug Chem Toxicol. 2022 Jan;45(1):143-150.
PMID: 31656113 [PubMed - indexed for MEDLINE]


Toxicological studies and bioactivity-guided identification of antimicrobially active compounds from crude aqueous stem bark extract of .
Dandashire BS, Magashi AM, Abdulkadir B, Abbas MA, Goni MD, Yakubu A

J Adv Vet Anim Res. 2019 Jun;6(2):183-192.
PMID: 31453189 [PubMed - as supplied by publisher]


Toxicological Assessment of a Standardized Gum Resin Extract.
Alluri VK, Dodda S, Kilari EK, Golakoti T, Sengupta K

Int J Toxicol. 2019;38(5):423-435.
PMID: 31234670 [PubMed - indexed for MEDLINE]


Assessment of toxicity and biochemical mechanisms underlying the insecticidal activity of chemically characterized Boswellia carterii essential oil against insect pest of legume seeds.
S K, Kujur A, Patel L, K R, Prakash B

Pestic Biochem Physiol. 2017 Jun;139():17-23.
PMID: 28595917 [PubMed - indexed for MEDLINE]


Defined Structure-Activity Relationships of Boswellic Acids Determine Modulation of Ca2+ Mobilization and Aggregation of Human Platelets by Boswellia serrata Extracts.
Siemoneit U, Tausch L, Poeckel D, Paul M, Northoff H, Koeberle A, Jauch J, Werz O

Planta Med. 2017 Aug;83(12-13):1020-1027.
PMID: 28403501 [PubMed - indexed for MEDLINE]


Pharmacokinetic and Pharmacodynamic Interaction of Boswellic Acids and Andrographolide with Glyburide in Diabetic Rats: Including Its PK/PD Modeling.
Samala S, Veeresham C

Phytother Res. 2016 Mar;30(3):496-502.
PMID: 26762235 [PubMed - indexed for MEDLINE]


Triggering of Suicidal Erythrocyte Death Following Boswellic Acid Exposure.
Calabrò S, Alzoubi K, Faggio C, Laufer S, Lang F

Cell Physiol Biochem. 2015;37(1):131-42.
PMID: 26303375 [PubMed - indexed for MEDLINE]


Acute and chronic toxicity, cytochrome p450 enzyme inhibition, and HERG channel blockade studies with a polyherbal, ayurvedic formulation for inflammation.
Dey D, Chaskar S, Athavale N, Chitre D

Biomed Res Int. 2015;2015():971982.
PMID: 25893199 [PubMed - indexed for MEDLINE]


Proulcerogenic effect of water extract of Boswellia sacra oleo gum resin in rats.
Asad M, Alhomoud M

Pharm Biol. 2016;54(2):225-30.
PMID: 25853959 [PubMed - indexed for MEDLINE]


Warfarin interactions with medicinal herbs.
Milić N, Milosević N, Golocorbin Kon S, Bozić T, Abenavoli L, Borrelli F

Nat Prod Commun. 2014 Aug;9(8):1211-6.
PMID: 25233607 [PubMed - indexed for MEDLINE]


Holy Saturday asthma.
O'Connor TM, Cusack R, Landers S, Bredin CP

BMJ Case Rep. 2014 Mar;2014():.
PMID: 24626388 [PubMed - indexed for MEDLINE]


Adverse effects of herbal medicines: an overview of systematic reviews.
Posadzki P, Watson LK, Ernst E

Clin Med (Lond). 2013 Feb;13(1):7-12.
PMID: 23472485 [PubMed - indexed for MEDLINE]


A-90 Day Gavage Safety Assessment of Boswellia serrata in Rats.
Singh P, Chacko KM, Aggarwal ML, Bhat B, Khandal RK, Sultana S, Kuruvilla BT

Toxicol Int. 2012 Sep;19(3):273-8.
PMID: 23293466 [PubMed - as supplied by publisher]


Safety Evaluation of Alcoholic Extract of Boswellia ovalifoliolata Stem-bark in Rats.
Devi PR, Adilaxmamma K, Rao GS, Srilatha Ch, Raj MA

Toxicol Int. 2012 May;19(2):115-20.
PMID: 22778507 [PubMed - as supplied by publisher]


Safety and toxicological evaluation of Aflapin: a novel Boswellia-derived anti-inflammatory product.
Krishnaraju AV, Sundararaju D, Vamsikrishna U, Suryachandra R, Machiraju G, Sengupta K, Trimurtulu G

Toxicol Mech Methods. 2010 Nov;20(9):556-63.
PMID: 20874664 [PubMed - indexed for MEDLINE]


Mutagenicity evaluation with Ames test of hydro-alcoholic solution of terpenes.
Lupi S, Marconi S, Paiaro E, Fochesato A, Gregorio P

J Prev Med Hyg. 2009 Sep;50(3):170-4.
PMID: 20411651 [PubMed - indexed for MEDLINE]


In vivo genotoxicity evaluation of a plant based antiarthritic and anticancer therapeutic agent Boswelic acids in rodents.
Sharma R, Singh S, Singh GD, Khajuria A, Sidiq T, Singh SK, Chashoo G, Pagoch SS, Kaul A, Saxena AK, Johri RK, Taneja SC

Phytomedicine. 2009 Dec;16(12):1112-8.
PMID: 19679457 [PubMed - indexed for MEDLINE]


Safety and Toxicological Evaluation of a Novel, Standardized 3-O-Acetyl-11-keto-beta-Boswellic Acid (AKBA)-Enriched Boswellia serrata Extract (5-Loxin(R)).
Lalithakumari K, Krishnaraju AV, Sengupta K, Subbaraju GV, Chatterjee A

Toxicol Mech Methods. 2006;16(4):199-226.
PMID: 20021046 [PubMed - as supplied by publisher]


Clastogenic effects of dietary supplement--Spirulina alga, and some medicinal plant products from Boswellia serrata, Withania somnifera on mice.
Ghoshal S, Mukhopadhyay MJ, Mukherjee A

Indian J Exp Biol. 2001 Oct;39(10):1068-70.
PMID: 11883518 [PubMed - indexed for MEDLINE]